Studies and Clinical Trials

SACRED ESSENCE™ ampoules submerged in water, showcasing the premium liquid supplement. The image features the blue ampoules highlighting the concentrated phycocyanin and magnesium-enriched formula. This visual emphasizes Recova’s focus on natural recovery supplements, high-concentration nutrients, and effective solutions for boosting energy and recovery."

Sacred Essence™

Sacred Essence™ is the world's only Spirulina extract to have been subjected to a double-blind, placebo-controlled clinical trial on humans. This clinical trial demonstrated, for the first time in humans, the antioxidant activity of a concentrated spirulina extract rich in phycocyanins and polysaccharides. It also highlighted a significant effect on reducing triglycerides and the Fatty Liver Index, indicating broad- spectrum functionality without toxicity.
Sacred Essence™ is currently undergoing a second clinical trial on humans, conducted in a hospitals setting on patients with cancer undergoing chemotherapy.

  • Graph Explanation

    This graph compares the effects of Sacred Essence™ and a placebo on three health parameters: Oxidative Stress, Triglyceride Levels, and the Fatty Liver Index.
    • Oxidative Stress: Sacred Essence™ led to a 13% reduction, while the placebo group saw almost no change.
    • Triglyceride Levels: Sacred Essence™ caused a 19% decrease in triglycerides, while the placebo group had no significant reduction.
    • Fatty Liver Index: Sacred Essence™ reduced this by 21%, compared to a slight 3% increase in the placebo group.

    Overall, the graph shows that Sacred Essence™ resulted in more significant improvements than the placebo across all three areas.

Efficacy of Sacred Essence in Reducing Oxidative Stress, Triglyceride Levels, and Improving Liver Health in Individuals with Metabolic Syndrome.

  • Clinical Study Design

    Type: Randomized, Double-Blind, Placebo-Controlled Trial

    • Duration: 6 weeks

    Participants

    • Inclusion Criteria:
    • Adults aged 30-65 years
    • Diagnosed with metabolic syndrome (meeting at least three of the following criteria: abdominal obesity, high triglycerides, low HDL cholesterol, high blood pressure, elevated fasting glucose)

    Randomization and Blinding

    • Participants will be randomly assigned to either the Sacred Essence or placebo group using a computer-generated randomization sequence.

    Monitoring:

    A Data Safety Monitoring Board reviews interim data to safeguard participant well-being and ensure the integrity of the study. Data collection follows standardized procedures and is managed in a secure electronic database

  • Percentage Results

    Reduction in Urinary Isoprostanes:

    • 13% decrease in urinary isoprostanes was observed, indicating a reduction in oxidative stress.

    Triglyceride Levels:

    • Decrease in Plasma Triglycerides:
    • 19% reduction in plasma triglyceride levels was noted in participants taking Sacred Essence 

    Fatty Liver Index (FLI):

    • Improvement in FLI:

    Participants experienced a 21% reduction in the Fatty Liver Index, indicating a potential improvement in liver health and a decrease in liver steatosis.

Study on Marine Magnesium

The study examines low magnesium levels in pregnant women at a hospital in Nigeria. It found that 16.25% of these women had low magnesium, which was linked to issues like pre-eclampsia (high blood pressure), leg cramps, and early labor. The researchers suggest that increasing magnesium intake through diet or supplements could help prevent these problems.

The study "Natural Magnesium-Enriched Deep-Sea Water Improves Insulin Resistance and the Lipid Profile of Prediabetic Adults: A Randomised, Double-Blinded Crossover Trial" investigated the effects of magnesium-rich deep-sea water on pre-diabetic adults. It found that consumption of this water significantly improved insulin resistance and lipid profiles, suggesting its potential as a natural intervention for managing pre-diabetes. The trial's double-blind, crossover design ensures robust results, highlighting the benefits of magnesium-enriched water in metabolic health.

SACRED SHINE™ ampoules submerged in water, showcasing the premium collagen magnesium supplement. The image features the elegant ampoules with bioactive collagen peptides and marine magnesium, emphasizing Recova’s focus on healthy ageing, joint support, and skin health through high-concentration nutrients and advanced formulation.

Sacred Shine™

The synergistic combination of Marine-sourced Magnesium and Cartidyss® - hydrolysed type II collagen peptides makesSacred Shine™a highly bioavailable and effective dietary supplement. It is 100% natural, and particularly efficient in improving joint comfort and reducing associated pain.
A study involving individuals aged 42-78 demonstrated significant benefits within 3 months. The group experienced a 50% reduction in joint pain and improved mobility by reducing cartilage inflammation.
Additionally, it visibly reduces wrinkles by 26% and plumps the skin by boosting elastin and hyaluronic acid production, improving skin density by 38% and thickness by 10%.
  • A graph showing the improvement in mobility from trials of Sacred Shine™. The graph highlights significant enhancements in joint flexibility and comfort, demonstrating the product's effectiveness in supporting joint health and mobility. Sacred Shine™, with its bioactive collagen peptides, is presented as a beneficial supplement for joint support and overall mobility improvement.

  • Graph Explanation:

    1. Reduction of Pain Over Time (Left Y-Axis, Red)

    Placebo Group:

    Represented by the red solid line with circles.

    Shows a gradual decrease in pain over the weeks from W2 to W8.

    Marine Collagen Group:

    Represented by the red dashed line with circles.

    Indicates a significant and more rapid reduction in pain compared to the placebo group, with pain levels dropping sharply by week W8.

    2. Improved Mobility Over Time (Right Y-Axis, Blue)

    Placebo Group:

    Represented by the blue solid line with crosses.

    Shows a slow and steady increase in weight-bearing capacity from W2 to W8.

    Marine Collagen Group:

    Represented by the blue dashed line with crosses.

Demonstrates a much steeper increase in weight-bearing capacity, reaching high levels by W6 and maintaining them through W8.

The graph clearly shows that Marine Collagen Hydrolysates are more effective than the placebo in both reducing pain and improving mobility over the eight-week period. The rapid improvement in the Marine Collagen group suggests significant benefits for joint health and muscle comfort.

A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Sacred Shine on Skin and Joint Health in Middle-Aged Adults

  • Study Design:

    • Double-blind, placebo-controlled, randomized clinical trial
    • Objective: Evaluate effectiveness of collagen peptides (PCP and BCP) for managing knee osteoarthritis (OA)
    • Primary endpoints: WOMAC, VAS, and QOL score changes from baseline to Week 13

    Participants:

    • 30 subjects (aged 30-65 years) diagnosed with knee OA
    • Visual analogue scale (VAS) score ≥40 and Kellgren-Lawrence grade 2-4
    • 7-day placebo run-in period prior to randomization

    Randomization and Blinding:

    • Computer-generated randomization using SAS® software
    • 2:1 randomization ratio: 20 subjects received PCP or BCP, 10 received placebo
    • Double-blinded study (neither participants nor researchers knew the group assignments)

  • Statistical Analysis:

    • Paired Student t-tests and Mann-Whitney U-tests applied
    • Confidence level: 95%
    • p < 0.01 considered statistically significant for comparing treatment groups and placebo

    Monitoring and Reporting:

    • Regular monitoring of safety, including blood and urine analyses
    • Vital signs (temperature, pulse rate, blood pressure) measured at each visit
    • Adverse events documented and managed appropriately

    Monitoring and Reporting
    Monitoring: An independent data monitoring committee (DMC) will oversee trial conduct and ensure participant safety.
    Reporting: Results will be published in peer-reviewed journals and presented at scientific conferences.
  • A graph illustrating the perceived skin benefits from trials of Sacred Shine™. The graph shows significant improvements in skin hydration, elasticity, and overall appearance as reported by participants. Sacred Shine™, featuring bioactive collagen peptides, is recognized for promoting skin health, making it a key supplement for healthy aging and enhancing skin vitality.

  • Graph Explanation:

    Cartidyss™ supports healthy skin aging. Cartidyss™ is composed of collagen peptides and glycosaminoglycans (GAGs) which are responsible for maintaining our skin structure, hydration, and its mechanical properties.A recent clinical study shows that after 90 days of supplementation at a low dosage (500mg/day) Cartidyss™:- Improves dermis density (collagen matrix) by 39% compared to placebo- Significantly reduces skin wrinkles- Improves skin flexibility and viscoelasticity- Tends to keep hydration in deeper skin layers- Tends to improve dermis hydration- Tends to reduce the size of the pores.

    Study proves 50% reduction in joint pain and improved mobility by reducing cartilage inflammation. Additionally, it visibly reduces wrinkles by 26% and plumps the skin by boosting elastin and hyaluronic acid production, improving skin density by 38% and thickness by 10%.

Downloadable links:

Studies on Cartidyss® Click Here

The study reviews how collagen supplements can help joint health. It found that certain types of collagen, like hydrolysed collagen peptides, can reduce joint pain and improve movement, especially for people with osteoarthritis. The research also points out that knowing the details of how these supplements are made and absorbed by the body is important for getting the best results.

Click here to read more

The study reviews how collagen hydrolysate (CH) can treat osteoarthritis (OA) and joint issues. CH, derived from collagen, has been shown to reduce pain and improve joint function by enhancing cartilage health and decreasing inflammation. Clinical trials in humans and animals support its potential as a safer alternative to traditional medications. However, more research is needed to fully understand its mechanisms and confirm long-term benefits.

Studies on Marine Magnesium:The study "Natural Magnesium-Enriched Deep-Sea Water Improves Insulin Resistance and the Lipid Profile of Pre-diabetic Adults: A Randomised, Double-Blinded Crossover Trial" investigated the effects of magnesium-rich deep-sea water on pre-diabetic adults. It found that consumption of this water significantly improved insulin resistance and lipid profiles, suggesting its potential as a natural intervention for managing pre-diabetes. The trial's double-blind, crossover design ensures robust results, highlighting the benefits of magnesium-enriched water in metabolic health.